Environmental Exposures, Diseases and Epigenetic Regulation: From Scientific Evidence to Prevention


Research Theme Summary

This workshop brought together experts from various fields, including public health, epidemiology, environmental economics, obesity, epigenetics, neurobiology, immunology, microbiota, and cancer. The goal was to form a research network to study the effects of diverse environmental exposures on human health in Chile and Sweden. We explored their connection to disease incidence and how to study and manage these environmental determinants. We shared experiences from both countries, focusing on public education, policy implementation, prevention strategies, and monitoring systems. This approach aims to foster future collaborative research and guide policy- making.


PIs

 

Carlos Guerrero Bosagna, Uppsala University

Marcela K. Sjöberg Herrera, P. Universidad Católica

 

Participants

 

Adan L. Martinez-Cruz, Swedish University of Agricultural Sciences

Estefania Andrea Nova Lamperti, Universidad de Concepción

Erick Marcelo Riquelme Sanchez, P. Universidad Católica

 
 

Víctor Cortés, P. Universidad Católica

Jorge Campusano, P. Universidad Católica

Peter Bergsten, Uppsala University

 
 

Maria Teresa Muñoz Quezada, Universidad de Chile

Sandra Cortés, P. Universidad Católica

Rodrigo Morales Castro, Karolinska Institute

 
 

Parisa Norouzitallab, Swedish University of Agricultural Sciences

Eduardo Villablanca, Karolinska Institute

 

Results

The workshop focused on three main topics to bridge the gap between scientific evidence and prevention of environmentally related diseases.

Firstly, we presented evidence on environmental exposures impacting human health in Chile and Sweden and deliberated strategies for reducing, monitoring, and regulating pollutants in both countries. This discussion encompassed Swedish government incentives that foster sustainable practices, leading to a decrease in the utilization or exposure reducing the adverse health effects. The necessity to broaden the range of pollutants monitored in Chile, legislate responsible concentration ranges, and adhere to laws and standards was underscored.

Secondly, we tackled communication strategies to articulate the impact of environmental exposures on health.

Thirdly, we contemplated the design and development of a scalable pilot study to map obesogenic environments. This considers the build-up of a model that includes individual assessments, environmental emissions as well as the territorial planification, socioeconomic factors and cost-benefit estimations of applying personalized interventions for maximum community impact.

The long-term objective would be to utilize this model to reshape areas to align with OECD standards and prevent environmental exposures affecting human health.